transgenicmice相关论文
Understanding normal and abnormal development of the Wolffian/epididymal duct by using transgenic mi
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Mar sequence carried by bicistron transfer body involves in enhancing and stabilizing follistatin ge
Due to public concerns about transgenic organisms, it is necessary to establish valid protocols for constructing vectors......
Behavior responses in APP/V717I transgenic mice with gender difference during AD pathology processin
Alzheimer disease(AD),one of the most common forms of dementia,is an age-dependent progressive neurodegenerative disorde......
目的 观察茵陈蒿汤及其变方对刀豆蛋白(ConA)诱导小鼠慢性免疫性肝损伤的 保护作用。方法选用BAB/c 小鼠70 只，雌雄各半，随机分为正......
Activation of b-catenin signaling in aggrecan-expressing cells in temporomandibular joint causes ost
Objective: β-catenin plays a critical role in cartilage formation and development.Dysregulation of β-catenin causes ca......
Neurodegeneration-like pathological and behavioral changes in an AAV9-mediated p25 overexpression mo
Background: The transgenic mice models overexpressing human p25 contribute greatly to the invivo neurotoxic mechanism of......
Centrosomal Nip is an oncogenic proteinthat is gene-amplified in human tumors and causes spontaneous
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Setting up breeding programs for transgenic mouse strains require to distinguish homozygous from the heterozygous transg......
Generation of Rm21LG transgenic mice: a powerful tool to generate conditional overexpression of miR-
miR-21 is highly expressed in a variety of cancers,suggesting that it might play a role in the process of oncogenesis,as......
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Suppression of induced atherosclerosis in h-apo AI transgenic mice by overexpression of human apo AI
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Effect of oxLDL on the uptake and clearance rate of cholesterol in v-SMC originated from human apoA1
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Synergistic function of Kras mutation and HBx in initiation and progression of hepatocellular carcin
Although the activation of Ras pathway is frequently observed in human hepatocellular carcinoma (HCC),the in vivo role o......
Objective: Nestin is a class Ⅵ intermediate filament protein that was originally described as a neuronal stem cell mark......
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Hypertrophic chondrocytes, which are the terminally differentiated form of chondrocytes, play a key role in endochon......
人工合成抗菌肽Thanatin基因的3条片段,利用重叠延伸PCR扩增技术得到完整的Thanatin基因,通过分子克隆方法构建出pIRES2-EGFP-Than......
BACKGROUND: Affected signal convection of synaptophysin on motor neurons may Cause injury of motor neurons and then indu......
AIM: To establish a mice model harboring hepatitis B virusx gene (adr subtype) for studying the function of hepatitis Bv......
Replication and gene expression of mutant hepatitis B virus in a transgenic mouse containing the com
AIM: To establish the transgenic mouse line harbouring complete hepatitis B virus (HBV) genome with mutant s gene (adr s......
AIM: To analyze the tissue morphologic phenotype and liver gene expression profile of hB1F transgenic mice.METHODS: Tran......
AIM: To evaluate the effects of animal milk containing fucosylated antigens on Helicobacter pylori (Hpylori) binding to ......
Therapeutic polypeptides based on HBcAg18-27 CTL epitope can induce antigen-specific CD8+ CTL-mediat
AIM: To explore how to trigger an HLAI-restricted CD8+ T cell response to exogenously synthesized polypeptides in vivo.M......
AIM: To study the inhibitory effect of oxymatrine on serum hepatitis B virus (HBV) DNA in HBV transgenic mice.METHODS: H......
AIM: To establish a mice model of hepatitis B by using HBV-transgenic mice, and to transfer HBV-specific cytotoxic T lym......
AIM: Human zinc finger protein 191 (ZNF191) was cloned and characterized as a Kruppel-like transcription factor, which m......
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AIM: To assess the combinative role of aflatoxin B1 (AFB1),cyanobacterial toxins (cyanotoxins), and hepatitis B virus (H......
Rescue of the albino phenotype by introducing a functional tyrosinase minigene into Kunming albino m
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目的建立TNNT3（R69H）突变转基因小鼠模型。方法构建pEGFP-TNNT3（R69H）转基因构件,通过原核显微注射方法将线性化、纯化后的外源质粒pEG......
试验研究了转基因小鼠建立中的受精卵显微注射和移植，对获得受精卵、有效注射及移植易出现的问题和解决讨论，对注射后的受精卵的移植......
